Dr. Nielen et al. have shown the feasibility for examining hair samples for anabolic steroids using DESI-MSn.  They combined the Omni Spray 1-D source with a Thermo Scientific LXQ linear ion trap mass spectrometer to record both full scan and data dependent MSn spectra of  hair samples.  The authors conclude that DESI-MSn analysis could be suitable for rapid screening for prioritizing samples for follow-up investigation. 
See:  Analytica Chimica Acta 700 (2011) 63-69.
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