Saturday, December 18, 2010

A recent publication on imaging human cancer tissue

Discrimination of Human Astrocytoma Subtypes by Lipid Analysis using Desorption Electrospray Ionization Imaging Mass Spectrometry

Livia S. Eberlin, Allison L. Dill, Alexandra J. Golby, Keith L. Ligon, Justin M. Wiseman, R. Graham Cooks, Nathalie Y. R. Agar,  Angewandte Chemie International Edition, 2010, 49, 5953-5956.


Differentiation of human brain astrocytic tumor grades can be achieved by direct lipid analysis using desorption electrospray ionization mass spectrometry (DESI-MS). Distinctive lipid profiles are associated with degree of malignancy, grades II, III, and IV.

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